Jak Knowles, M.D.
Chief Executive Officer
Robert Igarashi, Ph.D.
President and Co-Founder
Robert Igarashi, Ph.D. is the president and co-founder of CytoSen Therapeutics. Dr. Igarashi has a diverse background in life sciences and has played an instrumental role in the development of the particle based natural killer (NK) cell stimulating technology. He has brought his biochemical and physico-chemical expertise to combine with immunology for developing and refining the nanoparticle based method for NK cell stimulation that could be used for ex vivo expansion as well as in vivo stimulation of therapeutic NK cells.He has been crucial in understanding the biochemical aspects of the plasma membrane particles interacting with NK cells and how they can be further innovated to add novel therapeutic dimensions for adoptive NK cell therapy.
Dr. Igarashi joined the faculty at the University of Central Florida as an assistant professor in the Department of Chemistry with a joint appointment in the Burnett School of Biomedical Sciences. He is now a research scientist developing innovative methods for NK cell therapies. Dr. Igarashi achieved his B.S. and M.S. in biochemistry at California State University Fullerton and Ph.D. in biochemistry at Utah State University and was a postdoctoral scholar at University of California, Berkeley.
Dean Lee, M.D., Ph.D.
Vice President, Medical Director, Cofounder, and Chair of SAB
Dr. Lee has also developed genetic and non-genetic methods for improving tumor targeting and tissue homing of NK cells, leading to over a dozen invention disclosures, patents, and commercial licensing agreements.
In 2016, Dr. Lee joined Nationwide Children’s Hospital and The Ohio State University School of Medicine as professor of Pediatrics and director of the new joint Cellular Therapy and Cancer Immunotherapy Program. He serves as co-chair of the Cellular Therapy Working Group for the Pediatric Blood and Marrow Transplant Consortium, and is a member of the Cellular Therapy Steering Committee of the Children’s Oncology Group, the NIH Recombinant DNA Advisory Committee, and the NIH Gene Transfer Safety Assessment Board. Dr. Lee achieved his B.A. in Natural Sciences at Fresno Pacific College, his M.D. at Loma Linda University, and his Ph.D. in immunology at Loma Linda University.